Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress
Zhao J, Yu L, Xue X, Xu Y, Huang T, Xu D, Wang Z, Luo L, Wang H. Diminished α7 nicotinic acetylcholine receptor (α7nAChR) rescues amyloid-β induced atrial remodeling by oxi-CaMKII/MAPK/AP-1 axis-mediated mitochondrial oxidative stress. Redox Biol. 2023 Feb;59:102594.
小鼠
神經(jīng)疾病
2023
Epigallocatechin-3-gallate pretreatment alleviates doxorubicin-induced ferroptosis and cardiotoxicity by upregulating AMPK α 2 and activating adaptive autophagy
He H, Wang L, Qiao Y, Yang B, Yin D, He M. Epigallocatechin-3-gallate pretreatment alleviates doxorubicin-induced ferroptosis and cardiotoxicity by upregulating AMPKα2 and activating adaptive autophagy. Redox Biol. 2021 Nov 11;48:102185.
小鼠
心血管疾病
2021
Hepatic Acat2 overexpression promotes systemic cholesterol metabolism and adipose lipid metabolism in mice
Ma Z, Huang Z, Zhang C, Liu X, Zhang J, Shu H, Ma Y, Liu Z, Feng Y, Chen X, Kuang S, Zhang Y, Jia Z. Hepatic Acat2 overexpression promotes systemic cholesterol metabolism and adipose lipid metabolism in mice. Diabetologia. 2023 Feb;66(2):390-405.
小鼠
代謝疾病
2022
Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradation
Li T, Niu Z, Yu T, Li J, Lu X, Huang M, Wang Q, Yu X, Feng J, Xu B, Bing D, Li X, Lu L, Liang H, Yang R, Wang B, Shan H. Nucleosome assembly protein 1 like 1 (NAP1L1) promotes cardiac fibrosis by inhibiting YAP1 ubiquitination and degradation. MedComm (2020). 2023 Aug 15;4(5):e348.
小鼠
心血管疾病
2023
Fasting promotes acute hypoxic adaptation by suppressing mTOR-mediated pathways
Zhao R, Zhao X, Wang X, Liu Y, Yang J, Jiang S, Zhou X, Jiao B, Zhang L, Liu Y, Yu Z. Fasting promotes acute hypoxic adaptation by suppressing mTOR-mediated pathways. Cell Death Dis. 2021 Nov 3;12(11):1045.
大鼠
心血管疾病
2021
Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction
Yang H, He Y, Zou P, Hu Y, Li X, Tang L, Zhu Z, Tai S, Tu T, Xiao Y, Chen M, Wu C, Zhou S. Legumain is a predictor of all-cause mortality and potential therapeutic target in acute myocardial infarction. Cell Death Dis. 2020 Nov 26;11(11):1014.
小鼠
心血管疾病
2020